Resumen de MiRNAs in renal cell carcinoma

Jesús Miranda, Lucía Trilla Fuertes, Elena López Camacho, Andrea Zapater Moros, Rocío López Vacas, María Isabel Lumbreras Herrera, Ana Pertejo Fernández, Juan Ángel Fresno Vara, E. Espinosa Arranz, Angelo Gámez Pozo, Alvaro Pinto Marín

• MicroRNAs (miRNAs) are small RNA sequences that act as post-transcriptional regulatory genes to control many cellular processes through pairing bases with a complementary messenger RNA (mRNA). A single miRNA molecule can regulate more than 200 different transcripts and the same mRNA can be regulated by multiple miRNAs. In this review, we highlight the importance of miRNAs and collect the existing evidence on their relationship with kidney cancer.