Wentian Dong, Yong He, Jiuju Wang, Chuan Shi, Qihui Niu, Haokui Yu, Jun Ji, Xin Yu
Background and objectives To explore the discriminatory ability of a decision tree model based on cognitive testing data for the differential diagnosis of schizophrenia.
Methods This study enrolled 82 patients with schizophrenia and 82 patients with affective disorders. The cognitive function of the two groups of participants was assessed based on learning, symbol coding, digital span, trail making, and category fluency tests. The logistic regression model in the sklearn package in Python was applied to discriminate and analyse the data for all 11 variables in the MATRICS Consensus Cognitive Battery (MCCB).
Results The recognition rate for schizophrenia and affective disorder using all 11 variables of the MCCB was 82%.
Conclusion The logistics model based on cognitive data distinguished patients with schizophrenia from those with affective disorder.
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