The Royal Hospital of San Joseph de los Naturales in Mexico City was founded in the mid-16th century to provide medical and spiritual care to the Indians; its opening meant the creation of an institutional space in which the European and Mesoamerican medical systems were related. This article studies the political and social conditions that shaped this site and highlights the intercultural dialogue that took place inside it, which meant a fundamental contribution to the construction of a properly New Spain medical model.
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