Effect of Ischemia Times and Donor and Recipient Features on Maastricht Category III Kidney Transplant Outcomes

Iris Coello Torà; Ana Isabel Martínez Moreno; Maria Peraire Lores; Laura Aizpiri Antoñana; Camila Andrea Vega Vega; Miquel Amer Mestre; Ricardo José Guldris García; José Luis Bauzá Quetglas; Enrique Carmelo Pieras Ayala

Ayuda

Effect of Ischemia Times and Donor and Recipient Features on Maastricht Category III Kidney Transplant Outcomes

Iris Coello ^[1] ; Ana Isabel Martínez ^[2] ; Maria Peraire ^[2] ; Laura Aizpiri ^[2] ; Camila Andrea Vega ^[2] ; Miquel Amer ^[2] ; Ricardo José Guldris ^[2] ; Jose Luis Bauza ^[2] ; Enrique C. Pieras ^[2]
1. [1] Hospital Universitari de Tarragona Joan XXIII
  
  Hospital Universitari de Tarragona Joan XXIII
  
  Tarragona, España
2. [2] Hospital Universitario Son Espases
  
  Hospital Universitario Son Espases
  
  Palma de Mallorca, España
Localización: Archivos españoles de urología, ISSN 0004-0614, Tomo 75, Nº. 7 (September), 2022, págs. 612-617
Idioma: inglés
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Resumen
- Objective: Expansion of the donor pool has been enabled by the use of donation after circulatory death (DCD). The aim of this study is to identify what donation features are able to predict kidney transplant (KT) outcomes from DCD.
  
  Materials and Methods: A prospective analysis of all DCD KT from June 2016 to November 2019 was conducted. Association between donor and recipient features, and ischemia times with delayed graft function (DGF) and serum creatinine (Cr) at discharge, and at three and twelve months were analysed.
  
  Results: A total of 86 KT were performed. The results revealed a relationship between donor age (p = 0.014) and receptors on haemodialysis (p = 0.001) with DGF. There was no association between different ischemia times and DGF. Residual urine output greater than 500mL/day and being on peritoneal dialysis were found to be protective factors for DGF. Correlation analysis illustrated a significant correlation between donor age and Cr at discharge and at 3 months.
  
  Conclusion: Higher donor age and being on haemodialysis were risk factors for DGF. Likewise, donor age did not show a significant association with 12-month serum Cr. These results demonstrate that donor age is a risk factor for DGF but does not affect long term graft function.