The Inherited Hypercholesterolemias

• Wann Jia Loh ^[1] ; Gerald F. Watts ^[2]
  1. [1] Changi General Hospital

     Changi General Hospital

     Singapur

     
  2. [2] University of Western Australia

     University of Western Australia

     Australia

     
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 51, Nº. 3, 2022, págs. 511-537
• Idioma: inglés
• Enlaces
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• Resumen

  • Inherited hypercholesterolemias include monogenic and polygenic disorders, which can be very rare (eg, cerebrotendinous xanthomatosis (CTX)) or relatively common (eg, familial combined hyperlipidemia [FCH]). In this review, we discuss familial hypercholesterolemia (FH), FH-mimics (eg, polygenic hypercholesterolemia [PH], FCH, sitosterolemia), and other inherited forms of hypercholesterolemia (eg, hyper-lipoprotein(a) levels [hyper-Lp(a)]). The prevalence, genetics, and management of inherited hypercholesterolemias are described and selected guidelines summarized.