Síndrome DRESS causado por alopurinol y desencadenado por COVID-19

• Telma Elias ^[1] ; Ana Clara Dinis ^[1] ; Cátia Gorgulho ^[1]
  1. [1] Internal Medicine Department. Centro Hospitalar Médio Tejo
• Localización: Galicia Clínica, ISSN 0304-4866, ISSN-e 1989-3922, Vol. 82, Nº. 3 (Julio-Agosto-Septiembre), 2021, págs. 162-163
• Idioma: español
• Títulos paralelos:
  • Allopurinol-induced DRESS syndrome triggered by COVID-19
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• Resumen

  • Drug reaction with eosinophilia and systemic symptoms syndrome (DRESS Syndrome) is caused by many different aetiological factors. We present the case of a 56-year-old woman who started allopurinol treatment about 3 weeks before. She presented with fever, hypotension, tachycardia, generalized maculopapular cutaneous rash, facial edema and axillar, inguinal and cervical enlarged lymph nodes. Complementary diagnostic exams: slight lymphocytosis, eosinophilia, acute renal failure, elevated hepatic enzymes. Swab for SARS-CoV-2 was positive. Serologic tests for another virus were negative.

    Histopathological analysis was compatible with DRESS syndrome. SARS-CoV-2 could also be taken into account when suspected DRESS syndrome