Bioethics has revealed many fundamental concepts. Two of them are essential: vulnerability and dignity. Vulnerability is associated with the idea of integrity in the field of clinical research ethics, which begins at the second half of the twentieth century. From its part, dignity appears at the very origins of Western culture, in Classical Greece, and draws its contemporary sense from the Enlightenment. A brief, descriptive, and interpretive historical overview is made on the development of these two terms. Faced with the Covid-19 pandemic, their contemporary meaning is explained.
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