Preconception Counseling and Care for Pregnant Women with Thyroid Disease

• Autores: Rima K. Dhillon Smith, Kristien Boelaert
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 51, Nº. 2, 2022, págs. 417-436
• Idioma: inglés
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• Resumen

  • Women with overt thyroid disease should receive preconception counseling regarding the risks to pregnancy and fetal outcomes and be monitored regularly during pregnancy using appropriate reference ranges for thyroid function testing. Universal screening for thyroid dysfunction preconception or in early pregnancy is not currently recommended.

    Antithyroid drugs are the main treatment modality for hyperthyroidism in pregnancy and the dose and choice of medication requires careful consideration. Treatment strategies for subclinical hypothyroidism and isolated hypothyroxinemia and thyroid autoimmunity are still debated. Current evidence indicates that levothyroxine administration to euthyroid TPO antibody– positive women does not improve fertility and pregnancy outcomes