Desensitization to drugs in children

Luis Felipe Ensina ^[1] ; Mara Morelo Rocha Felix ^[2] ; Fernanda Sales da Cunha ^[2] ; Jean-Christoph Caubet ^[3]
1. [1] Universidade Federal de São Paulo
  
  Universidade Federal de São Paulo
  
  Brasil
2. [2] Universidade Federal do Estado do Rio de Janeiro
  
  Universidade Federal do Estado do Rio de Janeiro
  
  Brasil
3. [3] Geneva University Hospitals, Geneva, Switzerland
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Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 50, Nº. 2, 2022, págs. 48-57
Idioma: inglés
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Resumen
- Better knowledge and understanding about drug desensitization is required in the pediatric population, since there is little literature available about it and the most pediatric desensitization protocols have been adapted from adult instructions.
  
  Aiming to soften this issue and foster the future studies, this article presents a recent review about mechanisms of desensitization, diagnostic tools, and up to date management of drug hypersensitivity reactions in children. Bringing up an overview of pediatric hypersensitivity reactions to chemotherapy, biologic agents, antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines.