Resumen de On the use of texturized electrospun wound dressings for absorption maximization

Aitor Diaz Zelaia, Lorea Buruaga Lamarain, Judith Zubia Aranburu, Cristina Eguizabal Argaiz, Silvia Santos Cabrera, Clara Rodriguez Aierbe, Alaitz Zabala Eguren

• We have studied a new approach for maximizing the absorption capabilities of a wound dressing by using textured collectors in the electrospinning process. Thus, we aim to increase the surface to volume ratio of the mesh, obtaining a larger area to interact with the environment and to improve the healing process of a wound by a larger absorption rate of the dressing. To do so, a non-textured reference collector (2R BA Finish) and a textured collector (2M Linen Finish) from ACERINOX have been used in the electrospinning process. Then, the characterization of the fibers has been done using a scanning electron microscopy, followed by a surface analysis with an optical perfilometer, to ensure the geometries are correctly printed in the final mesh. An absorption test has been performed to see the improvement in the fluid uptake capabilities of the resultant dressings. The absorption capabilities of the textured dressings resulted to be a 90 percentage points bigger in low relative humidity manufacturing condition samples compared to the non-textured ones, whereas the fibers manufactured at high relative humidity conditions reported decreased absorption capabilities. Thus, a promising approach to increase the liquid uptake has been demonstrated that could improve the performance of wound dressings in wound healing processes.