Resumen de Synthesis, Antimicrobial Properties, and Biomedical Applicability of Ag(I) Cyanoximate Complexes
Karin J. Young, Laurel G. Habgood, Kristina L. Stensaas, Omar Villanueva, Willis Weigand
In this laboratory experiment, students evaluated three silver(I) complexes as potential additives for dental adhesives based on bacterial growth inhibition, heat stability, water insolubility, and cost-effectiveness. Each student prepared and analyzed a cyanoxime ligand and its corresponding silver(I) complex. Students characterized the antibacterial activity of the silver complexes against E. coli using a Kirby–Bauer disk-diffusion test. Laboratory data were shared among students to compare observed properties to determine which derivative is the most suitable. This multiweek experiment was used in inorganic chemistry laboratory courses to demonstrate the application of inorganic chemistry to biomedicine. The framework of the experiment was developed by a multi-institutional collaboration, and we highlight how the general procedures of the experiment were adapted to meet the needs of varying courses and contexts.
