Inspiratory Muscle Training on Glucose Control in Diabetes: A Randomized Clinical Trial

Mariana B. Pinto; Patrícia M. Bock; Andressa Schein; Juliana Portes; Raíssa B. Monteiro; Beatriz D. Schaan

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Inspiratory Muscle Training on Glucose Control in Diabetes: A Randomized Clinical Trial

Mariana B. Pinto ^[1] ; Patrícia M. Bock ^[3] ; Andressa Schein ^[2] ; Juliana Portes ^[1] ; Raíssa B. Monteiro ^[1] ; Beatriz D. Schaan
1. [1] Hospital de Clínicas de Porto Alegre
  
  Hospital de Clínicas de Porto Alegre
  
  Brasil
2. [2] Universidade Federal do Rio Grande do Sul
  
  Universidade Federal do Rio Grande do Sul
  
  Brasil
3. [3] Faculdades Integradas de Taquara, Taquara, Rio Grande do Sul, Brazil
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Localización: International journal of sport nutrition and exercise metabolism, ISSN 1526-484X, ISSN-e 1543-2742, Vol. 31, Nº. 1, 2021, págs. 21-31
Idioma: inglés
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Resumen
- This study evaluated the effects of inspiratory muscle training (IMT) in glucose control and respiratory muscle function in patients with diabetes. It was a randomized clinical trial conducted at the Physiopathology Laboratory of the Hospital de Clínicas de Porto Alegre. Patients with Type 2 diabetes were randomly assigned to IMT or placebo-IMT (P-IMT), performed at 30% and 2% of maximal inspiratory pressure, respectively, every day for 12 weeks. The main outcome measures were HbA1c, glycemia, and respiratory muscle function. Thirty patients were included: 73.3% women, 59.6 ± 10.7 years old, HbA1c 8.7 ± 0.9% (71.6 ± 9.8 mmol/mol), and glycemia 181.8 ± 57.8 mg/dl (10.5 ± 3.2 mmol/L). At the end of the training, HbA1c was 8.2 ±0.3% (66.1 ± 3.3 mmol/mol) and 8.7 ± 0.3% (71.6 ± 3.3 mmol/mol) for the IMT and P-IMT groups, respectively (p = .8). Fasting glycemia decreased in both groups with no difference after training although it was lower in IMT at 8 weeks: 170.0 ± 11.4 mg/dl(9.4 ± 0.6 mmol/L) and 184.4 ± 15.0 mg/dl (10.2 ± 0.8 mmol/L) for IMT and P-IMT, respectively (p < .05). Respiratory endurance time improved in the IMT group (baseline = 325.9 ± 51.1 s and 305.0 ± 37.8 s; after 12 weeks = 441.1 ± 61.7 s and 250.7 ± 39.0 s for the IMT and P-IMT groups, respectively; p < .05). Considering that glucose control did not improve, IMT should not be used as an alternative to other types of exercise in diabetes. Higher exercise intensities or longer training periods might produce better results. The clinical trials identifier is NCT 03191435.