Antifungal efficacy of chitosan nanoparticles against phytopathogenic fungi and inhibition of zearalenone production by Fusarium graminearum

• Abdel-Aliem, Hanem A. ; Gibriel, Ahmed Y. ; Rasmy, Nagwa M. H. ; Sahab, Ahmed F. ; El-Nekeety, Aziza A. ; Abdel-Wahhab, Mosaad Attia ^[1]
  1. [1] Food Toxicology & Contaminants Dept., National Research Center, Dokki, Cairo
• Localización: Comunicata Scientiae, ISSN-e 2177-5133, Vol. 10, Nº. 3, 2019 (Ejemplar dedicado a: Comunicata Scientiae), págs. 338-345
• Idioma: inglés
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• Resumen

  • Chitosan (COS) is a natural safe biopolymer that received great attention in agriculture, food, biomedical, pharmaceutical and environmental industries because their biocompatible, biodegradable, non-toxic and non-allergenic natures. The aims of the current study were to synthesize and characterize chitosan nanoparticles (COS-NPs), to evaluate their antifungal activity against phytopathogenic fungi and inhibition of zearalenone (ZEN) production by Fusarium graminearum. The results revealed that the deacetylation degree of COS was 86.9 0.44 %, the average of molar mass was 171.41 ± 0.29 g/mol, molecular weight was 244 ± 7 kDa and the concentration of free amino groups was 0.05 ± 0.019 mol L-1. COS-NPs showed the nanorod form with rough nature and particle size was around 180 nm. COS-NPs showed an excellent antifungal activity against Alternaria tenuis, Aspergillus niger, A. flavus, Baeuvaria bassiana, Fusarium graminearum, Fusarium oxysporum, Penicillium sp. and Sclerotium rolfsii in dose dependent manner. At a concentration of 800 ppm, it inhibits ZEN production by Fusarium graminearum. It could be concluded that COS-NPs are promise candidate as safe antifungal capable for the prevention of ZEN production.