Incidence and profile of benign epithelial tumors of salivary glands from a single center in Northeast of Brazil

Breno Washington Joaquim de Santana; Leorik-Pereira da Silva; Marianna-Sampaio Serpa; Mariana de Albuquerque Borges; Sérgio Ricardo Soares de Moura; Márcia María Fonseca Da Silveira; Ana Paula Veras Sobral

Ayuda

Incidence and profile of benign epithelial tumors of salivary glands from a single center in Northeast of Brazil

Breno Washington Joaquim de Santana ^[1] ; Leorik Pereira da Silva ^[2] ; Marianna Sampaio Serpa ^[3] ; Mariana de Albuquerque Borges ^[4] ; Sérgio Ricardo Soares de Moura ^[4] ; Márcia Maria Fonseca da Silveira ^[1] ; Ana Paula Veras Sobral ^[1]
1. [1] Universidade de Pernambuco
  
  Universidade de Pernambuco
  
  Brasil
2. [2] Universidade Federal do Amazonas
  
  Universidade Federal do Amazonas
  
  Brasil
3. [3] DDS, PhD, A.C.Camargo Cancer Center, São Paulo - SP, Brazil
4. [4] MD, Staff Pathologist, Department of Pathology, Cancer Hospital of Pernambuco, Recife, PE, Brazil
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Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 26, Nº. 1 (January), 2021
Idioma: inglés
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Resumen
- Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum. The aim was to determine the incidence and clinicopathological characteristics of benign salivary gland neoplasms diagnosed between 2007 and 2016 in a single center located in northeastern Brazil.
  
  Records regarding sex, age, anatomical location, histopathological subtype and treatment were retrieved, and data were analyzed using the Stata/IC software (version 12.0).
  
  There were above 7,100 cases of neoplasms in the head and neck region, of which 403 corresponded to salivary gland neoplasms. Of these, 238 (59%) were benign, being pleomorphic adenoma (PA) the most frequent neoplasm (n=178; 74.8%), followed by Warthin's tumor (WT) (n=23; 9.7%). Overall, most cases occurred in females (n=136; 57.1%) and age ranged from 11 to 83 years. The parotid gland (n=188; 79%) was the most common anatomical site, and all patients were treated by surgical excision. Of the cases diagnosed as PA, malignant transformation to carcinoma ex-pleomorphic adenoma (CAEXPA) occurred in 7 (3.9%) cases.
  
  The present study confirmed the clinical and demographic profile of benign salivary gland neoplasms, which contributes to the continuous knowledge of current data about these lesions.