The link between astrology and medicine is mentioned by Llull several times in the Tractatus novus de astronomia, and is regarded as the central theme of the Liber de regionibus sanitatis et infirmitatis. This feature of his thought, which takes up a current element in the scholastic and medical culture of his time, was perceived and valued in the context of Renaissance Lullism, as shown by some manuscripts from the 15th century on, as well as by the Explanatio compendiosaque applicatio artis Lulli by Bernardus de Lavinheta, which has the Liber de regionibus as the fulcrum of its medical section. However, only Giordano Bruno focuses explicitly on this Lullian work (which he read in the Explanatio), recognizing the relationship between macrocosm and microcosm as its core, and identifying the instrument to descend from universal principles to the specific particular (ad praxin) in the medical-astronomical figure that Lavinheta had built upon the figures of Llull, reproduced and analysed in his Medicina Lulliana.
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