¿De-evolution¿ of Drosophila toward a more generic mode of axis patterning

• Autores: Claude Desplan, Jeremy Lynch
• Localización: International journal of developmental biology, ISSN 0214-6282, Vol. 47, Nº. 7-8, 2003, págs. 497-503
• Idioma: inglés
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• Resumen

  • The genetics of the establishment of the primary axes of the early embryo have been worked out in great detail Drosophila. However, evidence has accumulated that Drosophila employs a mode of patterning that is not shared with most insects. In particular, the use of the morphogenic gradient of the Bicoid homeoprotein appears to be a novel addition to the fly developmental toolkit. To better understand the ancestral mode of patterning that is probably more widely used by insects, several groups have used Evo-Devo approaches as well as sophisticated genetic manipulations of Drosophilato achieve some form of ¿de-evolution¿ of this derived insect. Genetic manipulations of the beetle Tribolium and the wasp Nasonia have validated most of these results.