In vitro antibacterial efficacy of a new chlorhexidine slow-release device

• Autores: Shaul Lin, Liran Levin, Ervin Izhak Weiss, Micha Peled, Zvi Fuss
• Localización: Quintessence International, ISSN-e 0033-6572, Vol. 37, Nº. 5, 2006, págs. 391-394
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Objective: The aim of this study was to evaluate and compare the antibacterial effect of chlorhexidine and calcium hydroxide slow-release devices on oral bacteria. Method and Materials: The agar diffusion test was used to evaluate the antibacterial effect of the slow-release devices Activ Point (chlorhexidine; Roeko) and Calcium Hydroxide Plus Point (Roeko) on 8 anaerobic and 2 facultative oral bacterial strains, as well as 2 bacterial cultures randomly sampled from necrotic root canals and incubated in anaerobic and aerobic broth for 48 hours. The efficiency of the medicaments against the various strains was evaluated using a nonparametric test (Friedman type) and a second nonparametric test (Wilcoxon's signed rank test). Results: Activ Point produced significantly larger inhibition zones (P < .001) than the calcium hydroxide slow-release device around all tested bacterial strains. Conclusion: The chlorhexidine slow-release device (Activ Point) exhibited significant antibacterial activity in the agar diffusion test and merits study as an intracanal medicament.