Resumen de Reporte de un caso: Glomeruloesclerosis focal y segmentaria con examen de orina normal
Melisa Palacios Guillen, Carmen Asato Higa, Julia Sumire Umaru, Jimy Henry Álvarez Mayorga
- español
La glomeruloesclerosis focal y segmentaria (GEFS) tiene presentación clínica con edemas, examen de orina anormal y disminución variable de la función renal. Se presenta el caso de una paciente de 23 años, sin antecedentes de importancia, con 1 año y medio presentando edema de miembros inferiores, cara y tórax; disminución del volumen urinario que dura un mes, mejora con diuréticos y reaparece a los 2 meses. En el examen se encuentra edema palpebral y en piernas. Exámenes auxiliares: creatinina normal, depuración de creatinina 61ml/min, orina normal, proteinuria normal, ANA, AntiDNA, hepatitis y HIV negativos, C3 normal, ecografía renal normal. Se realizó Biopsia Renal que mostró ocho de veinte glomérulos alterados, compatible con GEFS.
- English
The clinical presentation of focal and segmental glomerulosclerosis (FSGS) includes edema, an abnormal urine examination, and variably decreased kidney function. A twenty three year-old female patient, with a non-remarkable medical history developed during the last 18 months lower extremity, facial, and chest wall edema, and decreased urinary output that improved with the use of diuretics, but after two months she had a recurrence of her symptoms. Physical examination revealed the presence of eyelid and leg edema. Relevant laboratory tests showed normal creatinine values, creatinine clearance 61 mL/min, normal urinalysis, normal proteinuria; ANA, anti-DNA, hepatitis and HIV tests were reported as negative. C3 was also normal, as well as kidney ultrasonography. A kidney percutaneous biopsy was performed, which showed 8/20 affected glomeruli, and focal and segmental glomerulosclerosis.
