Presence of Trichomonas spp. in oral ulcerations of a patient with kidney transplant. A case report

• Ganna Dmytrenko ^[2] ; Lorena Tana ^[3] ; María-Victoria Cachau ^[4] ; Martín Bravo ^[3] ; Silvina Gonzalez ^[5] ; Fernando Correa ^[1] ; Javier Fernandez-Solari ^[1] ; Andrea De Laurentiis ^[2]
  1. [1] Universidad de Buenos Aires

     Universidad de Buenos Aires

     Argentina

     
  2. [2] Centre of Pharmacological and Botanical Studies, CEFYBO-CONICET-UBA, School of Medicine, University of Buenos Aires, Argentina; Physiology Dept., School of Dentistry, University of Buenos Aires, Argentina; National Scientific and Technical Research Council (CONICET), Argentina
  3. [3] High Complexity Transplant Institute, Nephrology Argentina
  4. [4] Pathology Dept., José de San Martín Clinical Hospital, Buenos Aires, Argentina
  5. [5] Stomatology Dept., José de San Martín Clinical Hospital, Buenos Aires, Argentina

  Mostrar afiliaciones +
• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 12, Nº. 12 (December), 2020, págs. 1201-1205
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Mucosal ulcerations are an oral complication that can often affect kidney transplant patients, mostly due to the effect of immunosuppression. It has been frequently reported drug-induced ulceration or lymphoproliferative disorders with buccal manifestations however, some unusual disorders should also be considered, such as fungal infections, viruses, as well as opportunistic infection by other microorganisms. Determining the etiology and differential diagnose from other causes of mouth ulcers is very important for the adequate treatment of said lesion. Dental health of patients should also be taken into the account prior to the transplant surgery, since periodontal pockets are the main niche of microbial reservoir. Moreover, mixed with oral microbiota, parasites such as Trichomonas spp. can be found in the dental plaque of patients with periodontal disease. Particularly, Trichomonas spp. are anaerobic motile-flagellated protozoa that can both induce tissue damage and exacerbate preexistent injuries in vaginal and oral mucosa. Parasitic infection in the oral cavity has not been well studied and it is thought to be underreported. In the present study we report the first case in literature of presence of Trichomonas spp. as a potential etiological factor of the oral ulcerations of a kidney transplanted patient that remitted after antibiotic treatment.