Pediatric Type 2 Diabetes: Not a Mini Version of Adult Type 2 Diabetes

• Autores: Talia Alyssa Savic Hitt, Lorraine E. Levitt Katz
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 49, Nº. 4, 2020 (Ejemplar dedicado a: Pediatric Endocrinology), págs. 679-693
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Pediatric type 2 diabetes mellitus (T2DM) is increasing in incidence, with risk factors including obesity, puberty, family history of T2DM in a first-degree or second-degree relative, history of small-for-gestational-age at birth, child of a gestational diabetes pregnancy, minority racial group, and lower socioeconomic status. The pathophysiology of T2DM consists of insulin resistance and progression to pancreatic beta-cell failure, which is more rapid in pediatric T2DM compared with adult T2DM. Treatment options are limited. Treatment failure and nonadherence rates are high in pediatric T2DM; therefore, early diagnosis and treatment and new pharmacologic options and/or effective behavioral interventions are needed. © 2020 Elsevier Inc.