An image created by Nick Moser and Chris Bakal of a metastatic melanoma cell is presented. They used scanning electron microscopy to create the shot, shortlisted in this year's Institute of Cancer Research (ICR) Science and Medical Imaging competition. This contest is a chance for staff at the ICR and the Royal Marsden NHS Foundation Trust to showcase their work. Moser and Bakal used an ion beam to blast the cell, creating a triangular shape as the beam cut the cell and the silica substrate it grew on. This gives researchers an unprecedented view of the cell. Melanoma cells attach to surfaces using focal adhesions--structures that they make to interact with their surroundings. Removing part of the cell shows what happens as these form. The spread of cancer cells to other parts of the body is especially dangerous, so understanding how they attach to various tissues is vital.
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