Acinar cell carcinoma of the pancreas. A histologic, immunocytochemical and ultrastructural study

• Caruso, R.A. ^[1] ; Inferrera, A. ^[1] ; Tuccari, G. ^[1] ; Barresi, G. ^[1]
  1. [1] University of Messina,Italy
• Localización: Histology and histopathology: cellular and molecular biology, ISSN-e 1699-5848, ISSN 0213-3911, Vol. 9, Nº. 1, 1994, págs. 53-58
• Idioma: inglés
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• Resumen

  • A rare of acinar cell carcinoma of the pancreas is presented. Because of it unusual solid growth pattern, correct diagnosis required electron microsocopic analysis and the demosnstration of intracellular amylase by immunohistochemicasl stains. The presence of pleomorphic electron-dense cytoplasmic granules containing fibrillary internal structures is confirmed in this ultrastructural study. The differnetial diagnosis of acinar cell carcinoma from other neoplasms involving the pancreas, including neuroendocrine tumours, poorly-differentiated adenocarcinomas and neoplasms of putative acinar cell derivations, is discussed.