DNA synthesis in the embryonic chick lens epithelium is arrested after experimental lens rotation

• Prada, F. A. ^[1] ; Garcia-Lomas, V. ^[1] ; Genís-Gálvez, J. M. ^[1]
  1. [1] Universidad de Sevilla

     Universidad de Sevilla

     Sevilla, España

     
• Localización: Histology and histopathology: cellular and molecular biology, ISSN-e 1699-5848, ISSN 0213-3911, Vol. 9, Nº. 1, 1994, págs. 45-48
• Idioma: inglés
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• Resumen

  • Using autoradiographic technique, we have studicd DNA synthesis in normal embryonic chick lens epitheliuni and after experimental lens rotation. Analysis of the autoradiograms clearly demonstrates that when the lens priniordium was rotated 180". so that lens epithelium was placed facing the interior of the optic cup. the lens epithelial cells completely stop DNA synthesis. This fact suggests that some retinal and vitieal factors are responsible for differentiation and replicative capacity of the lens epithelial cells.