Unravelling Microbial Communities with DNA-Microarrays: Challenges and Future Directions

• Michael Wagner ^[1] ; Hauke Smidt ^[2] ; Alexander Loy ^[1] ; Jizhong Zhou ^[3]
  1. [1] University of Vienna

     University of Vienna

     Innere Stadt, Austria

     
  2. [2] Wageningen UR

     Wageningen UR

     Países Bajos

     
  3. [3] University of Oklahoma

     University of Oklahoma

     Estados Unidos

     

  Mostrar afiliaciones +
• Localización: Microbial ecology, ISSN-e 1432-184X, ISSN 0095-3628, Vol. 53, Nº. 3, 2007, págs. 498-506
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • High-throughput technologies are urgently needed for monitoring the formidable biodiversity and functional capabilities of microorganisms in the environment. Ten years ago, DNA microarrays, miniaturized platforms for highly parallel hybridization reactions, found their way into environmental microbiology and raised great expectations among researchers in the field. In this article, we briefly summarize the state-of-the-art of microarray approaches in microbial ecology research and discuss in more detail crucial problems and promising solutions. Finally, we outline scenarios for an innovative combination of microarrays with other molecular tools for structure-function analysis of complex microbial communities.