Ewing’s sarcoma of the cervix: a case report and review of literature

• Yangyang Zhang ^[1] ; Weixia Nong ^[2] ; Yan Ren ^[1] ; Jinfang Jiang ^[1] ; Haijun Zhang ^[1] ; Lian Meng ^[1] ; Qianru Li ^[1] ; Qiaochu Zhang ^[1] ; Xiaomeng Wang ^[1] ; Yang Wang ^[1] ; Chunxia Liu ^[1] ; Feng Li ^[1]
  1. [1] Shihezi University

     Shihezi University

     China

     
  2. [2] The First Affiliated Hospital of Medical College of Shihezi University, Shihezi, Xinjiang, PR China
• Localización: Histology and histopathology: cellular and molecular biology, ISSN-e 1699-5848, ISSN 0213-3911, Vol. 35, Nº. 5, 2020, págs. 475-480
• Idioma: inglés
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• Resumen

  • Ewing’s sarcoma (ES) is a small cell malignant tumor that occurs in the bone of children or adolescents. ES can also occur in extraskeletal organs, such as the pancreas, thyroid, liver, proximal phalanx, and, rarely, cervix. Only 15 published case reports have discussed ES arising in the cervix. We report a 76-yearold woman who had groin mass. ES was diagnosed in accordance with morphological and immunohistochemical maps. Fluorescence in situ hybridization and RT-PCR (reverse transcription PCR) revealed ESWR1 gene rearrangement and fusion gene formation (EWSFLI- 1), both of which confirmed the diagnosis of ES.

    Although the patient underwent surgical resection, the patient died without chemotherapy and radiotherapy.

    This case is the first one to involve a patient aged over 70 years and the fifth one to show metastasis occurrence.