Resumen de Ozone therapy in the treatment of the neuroinfectious diabetic foot. Case report

Adriana Schwartz Tapia, Hilda G. Rivera Bardales, Blanche Talbott

• Given the proven therapeutic effects of the medical ozone in Diabetes Mellitus (DM) especially in the management of neuroinfectious diabetic foot as adjuvant treatment, it is chosen as a first-line therapy to treat the case of a female patient with a neuroinfectious diabetic foot with osteomelitis and in sepsis.

  The biological effects of ozone therapy at clinical level are already well known; among its main properties are: to combat oxidative stress, the immunomodulatory effect and the germicidal effect against bacteria, viruses, protozoa and fungi. On the other hand, it is known that among the complications of the diabetic patient are neuroinfectious diabetic foot, immunodeficiency and septic state which in this case seriously compromised the life of the patient object of this report.

  The female patient entered the clinic in a state of semi-consciousness, confused, erratic and diagnosed with neuroinfectious diabetic foot, with septic lesions and necrosis of the fourth finger and dorsal side of the right foot through which emanated fetid pus in abundant quantity. Bone, tendons and muscles were visualized. Her general condition was very compromised, in sepsis. She was treated with antibiotic therapy, combined with systemic ozone therapy treatment, using ozonized saline solution (SSO3) at high doses twice a day, and ozone bag at high concentrations twice a day with catheter placement in the dorsal fistula of the right foot, through which the bone was directly ozonized. Once the sepsis and metabolic state were under control the following step was to apply daily rectal insufflations, in combination with local therapy with ozone bags, as well as the topical application of IP 800 ozonated oil, obtaining satisfactory results, from the systemic point of view of its septic disorder as local.

  The patient evolved satisfactorily, saving herself from imminent death and safe the amputation of the limb. She was discharged after six months with complete restoration of her injuries and absolute control of her diabetes. The treatment was performed on an outpatient basis.