A guide to naming human non‐coding RNA genes

• Ruth L Seal ^[1] ; Ling‐Ling Chen ^[4] ; Sam Griffiths‐Jones ^[2] ; Todd M Lowe ^[3] ; Michael B Mathews ^[5] ; Dawn O'Reilly ^[6] ; Andrew J Pierce ^[7] ; Peter F Stadler ^[8] ; Igor Ulitsky ^[9] ; Sandra L Wolin ^[10] ; Elspeth A Bruford ^[1]
  1. [1] University of Cambridge

     University of Cambridge

     Cambridge District, Reino Unido

     
  2. [2] University of Manchester

     University of Manchester

     Reino Unido

     
  3. [3] University of California, Santa Cruz

     University of California, Santa Cruz

     Estados Unidos

     
  4. [4] 3 State Key Laboratory of Molecular Biology Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Science Shanghai China
  5. [5] 6 Department of Medicine Rutgers New Jersey Medical School Newark NJ USA
  6. [6] 7 Computational Biology and Integrative Genomics Lab MRC/CRUK Oxford Institute and Department of Oncology University of Oxford Oxford UK
  7. [7] 8 Translational Medicine Oncology R&D AstraZeneca Cambridge UK
  8. [8] 9 Bioinformatics Group Department of Computer Science Interdisciplinary Center for Bioinformatics University of Leipzig Leipzig Germany; 10 Max Planck Institute for Mathematics in the Sciences Leipzig Germany; 11 Institute of Theoretical Chemistry University of Vienna Vienna Austria; 12 Facultad de Ciencias Universidad National de Colombia Sede Bogotá Colombia; 13 Santa Fe Institute Santa Fe USA
  9. [9] 14 Department of Biological Regulation Weizmann Institute of Science Rehovot Israel
  10. [10] 15 RNA Biology Laboratory National Cancer Institute National Institutes of Health Frederick MD USA

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• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 39, Nº. 6, 2020
• Idioma: inglés
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  • Research on non‐coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, http://www.genenames.org) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.