A high salivary calcium concentration is a protective factor for caries development during orthodontic treatment

• Andreia-Alves Cardoso ^[1] ; Emerson-Tavares de Sousa ^[1] ; Carolina Steiner-Oliveira ^[1] ; Thaís-Manzano Parisotto ^[2] ; Marinês Nobre-dos-Santos ^[1]
  1. [1] Department of Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba-SP, Brazil
  2. [2] Laboratory of Microbiology and Molecular Biology, Dental School, São Francisco University, Bragança Paulista – SP, Brazil
• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 12, Nº. 3 (March), 2020, págs. 209-214
• Idioma: inglés
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• Resumen

  • This research aimed to evaluate the salivary concentrations of fluoride (F-), calcium (Ca2+), and phosphate (Pi) after brackets bonding, and to identify the role of [F-], [Ca2+], and [Pi] on the development of active caries lesion (ACL) in individuals under fixed orthodontic treatment.

    A longitudinal investigation with twenty-two individuals from 11 to 22 years of age was performed in four phases (baseline and after 1, 3, and 6 months). Analyses were carried out considering the salivary concentration of [F-], [Ca2+], and [Pi], as well as the caries index. Data were analyzed using the Friedman test, followed by the Wilcoxon test and the multivariate Cox model (p≤0.05).

    1 and 3 months after appliance bonding, the [Ca2+] was statistically lower than after 6 months (p<0.0083). On the other hand, salivary [F-] and [Pi] did not show any significant difference during the follow-up. The Cox model demonstrated that the increase of 1 µg/mL in Ca2+ decreased the risk of ACL development by 27%. In conclusion, the levels of Ca2+ changed during orthodontic treatment.

    A high Ca2+ level in the saliva is a protective factor for ACL development over time.