Gestational Diabetes Mellitus

• Autores: Emily D. Szmuilowicz, Jami L. Josefson, Boyd E Metzger
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 48, Nº. 3, 2019 (Ejemplar dedicado a: Pregnancy and Endocrine Disorders), págs. 479-493
• Idioma: inglés
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• Resumen

  • Although it has been accepted for decades that women with gestational diabetes mellitus (GDM) are at high risk for future development of type 2 diabetes, vigorous debate regarding the value of detecting and treating GDM has persisted into the twenty-first century. Although results from 2 randomized trials provide strong evidence that treating GDM reduces adverse perinatal outcomes, it remains to be determined whether treatment impacts long-term offspring outcomes. Insulin is the first-line pharmacologic treatment and is added when glycemic goals are not met with nutritional modifications. Oral agent use is controversial, as data on long-term offspring outcomes are lacking.