Detection and Classification of Ignitable Liquid Residues in the Presence of Matrix Interferences by Using Direct Analysis in Real Time Mass Spectrometry,

• Barnett, Isabella ^[1] ; Bailey, Frank C. ^[2] ; Zhang, Mengliang ^[2]
  1. [1] Middle Tennessee State University

     Middle Tennessee State University

     Estados Unidos

     
  2. [2] Tennessee State University

     Tennessee State University

     Estados Unidos

     
• Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 64, Nº. 5, 2019, págs. 1486-1494
• Idioma: inglés
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• Resumen

  • Conventional Gas Chromatography-Mass Spectrometry (GC-MS) methods for the analysis of ignitable liquids (ILs) are usuallytime-consuming, and the data produced are difficult to interpret. A fast IL screening method using direct analysis in real time mass spectrome-try (DART-MS) is proposed in this study. GC-MS, QuickStrip DART-MS, and thermal desorption DART-MS methods were used to analyzeneat ILs and thermal desorption DART-MS without extraction was used to analyze ILs on five substrates (e.g., carpet, wood, cloth, sand, andpaper). Compared to GC-MS, DART-MS methods generated different spectral profiles for neat ILs with more peaks in the higher mass rangeand also provided better detection of less volatile compounds. ILs on substrates were successfully classified (98+-1%) using partial leastsquares discriminant analysis (PLS-DA) models based on thermal desorption DART-MS data. This study shows that DART-MS has greatpotential for the high-throughput screening of ILs on substrates.