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Development of a tool for screening adverse food reactions and food allergy in Portuguese children

    1. [1] Universidade da Beira Interior

      Universidade da Beira Interior

      Covilhã (Conceição), Portugal

    2. [2] Hospital Center of Cova da Beira

      Hospital Center of Cova da Beira

      Covilhã (Conceição), Portugal

    3. [3] Hospital Universitario de Salamanca

      Hospital Universitario de Salamanca

      Salamanca, España

    4. [4] Universidade Federal de Pernambuco

      Universidade Federal de Pernambuco

      Brasil

  • Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 47, Nº. 4, 2019, págs. 342-349
  • Idioma: inglés
  • Texto completo no disponible (Saber más ...)
  • Resumen
    • Introduction and objectives A standardised questionnaire may be an excellent tool for epidemiological studies aiming at screening children with suspected food allergies. Thus, the aim of the present study was to develop a screening questionnaire for assessing children with suspected food allergy and to analyse its reproducibility.

      Materials and methods A questionnaire of adverse food reactions was developed by literary review of similar questionnaires validated in other countries as well as less well defined, non-validated Portuguese questionnaires. Peer review of the questionnaire by a panel of specialists and subsequent exploratory analysis was carried out by applying the questionnaire in children with confirmed food allergy. Test–retest analysis was performed by giving a face-to-face questionnaire to 159 children with suspected adverse food reactions, aged between three and 11 years. Temporal stability using Spearman Rho correlation test and reproducibility was studied using Cohen's Kappa index.

      Results 115 children confirmed adverse food reactions that occurred with one or more foods. Retest was given about three weeks after the test, to 50 of these children who were randomly selected. The questionnaire showed good temporal stability (Spearman correlation coefficient of 0.834), and good reproducibility (only two of the 27 items had a Kappa index <0.60).

      Conclusions This questionnaire showed good temporal stability and reproducibility. Its validation for screening children with suspected food allergy will allow a standardised approach to diagnosis and comparison of results obtained in different centres.


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