Does the MHC confer protection against malaria in bonobos?

• Autores: Natasja G. de Groot, Jeroen M. G. Stevens, Ronald E. Bontrop
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 39, Nº. 10, 2018, págs. 768-771
• Idioma: inglés
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• Resumen

  • The immunological factors that could explain the near absence of malaria parasites in bonobos are not yet understood. The MHC class I system, however, may play an important role, as particular bonobo allotypes show functional similarities to HLA-B*53/B*78, which are considered to confer protection against malaria in humans