Tissue unit-ed: lung cells team up to drive alveolar macrophage development

• Charlotte L. Scott ^[1] ; Martin Guilliams ^[1]
  1. [1] Ghent University

     Ghent University

     Arrondissement Gent, Bélgica

     
• Localización: Cell, ISSN 0092-8674, Vol. 175, Nº. 4, 2018, págs. 898-900
• Idioma: inglés
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• Resumen

  • Using single-cell RNA sequencing of both immune and non-immune cells in the developing lung, Cohen et al. map candidate cell-cell interactions during alveolar macrophage development. This revealed potential cross-talk between epithelial cells, ILC2s, basophils, and the developing macrophages, which were validated both in vitro and in vivo.