Web of autism genes pinpoints key players

• Autores: Douglas Heaven
• Localización: New scientist, ISSN 0262-4079, Nº. 2921, 2013, pág. 12
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Caleb Webber at the University of Oxford and his colleagues created the largest interacting network yet of genes linked to autism. The team looked at the DNA of 181 individuals with autism and found they often had either many more or many fewer copies of certain genes known to be important for the transmission of brain signals, a system thought to go awry with autism. By feeding these genes into a computer model and tracing their interactions, they were able to build a web-like network, with genes in the center having many connections and those at the edge just a few. They found that many of the genes identified in the 181 people were connected to others that had previously been linked to autism.