Improved Procedure for Bleach-Based Alcohol Oxidation in Undergraduate Laboratories

• Edon Vitaku ^[1] ; Hamish S. Christie ^[1]
  1. [1] University of Arizona

     University of Arizona

     Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 96, Nº 5, 2019, págs. 1042-1045
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A reliable method for bleach-based alcohol oxidation has been developed. Use of sodium bisulfate as the acid additive in the reaction mixture eliminates the various problems associated with acetic acid, which has commonly been used for this type of oxidation. By conducting the reaction in an ethyl acetate/water two-phase reaction mixture, efficient reaction occurs at room temperature, and the workup is straightforward. This more reliable version of the well-known transformation has been successfully performed by thousands of second-year undergraduate organic chemistry students over the last several years.