A. Esteves, J Viegas Fernandes, M.R. Pastorinho, O. Lourenço, A.M. Fonseca, E.M. Cardoso, L. Granadeiro, F.A. Arosa, A.J. Santos Silva, Patrícia Padrão, A. Sousa Gomes, Luis Taborda Barata
Background Chronic rhinitis / rhinosinusitis (CRS) is associated with inflammation of the nasal and perinasal mucosa, with subsequent clinical symptoms.
Sulfurous (natural mineral) thermal waters (STW) have been used as complementary therapeutic approach to CRS, with studies demonstrating clinical efficacy.
However, few prospective, randomised, double-blind, placebocontrolled studies have been developed in order to assess clinical efficacy and none has been implemented in Portugal. Furthermore, worldwide, there is scant information of the modulatory effects STW crenotherapy may have on immune-inflammatory aspects underlying CRS.
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