Effect of 8 Weeks of Hospital-Based Resistance Training Program on TCD4+ Cell Count and Anthropometric Characteristic of Patients With HIV in Tehran, Iran: A Randomized Controlled Trial
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Morteza Ghayomzadeh [1] ; Seyedahmad Seyedalinaghi [2] ; Mahdieh M. Shamsi [1] ; Sajjad Rezaei [1] ; Conrad P. Earnest ; Sima Akbarnejad [3] ; Leila Taj [2] ; Minoo Mohraz [2] ; James W. Navalta ; Peyman Ghasemi [1] ; Fabrício Azevedo Voltarelli
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[1] Tarbiat Modares University
Tarbiat Modares University
Irán
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[2] Tehran University of Medical Sciences
Tehran University of Medical Sciences
Irán
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[3] University of Shahid Beheshti, Tehran
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- Localización: Journal of strength and conditioning research: the research journal of the NSCA, ISSN 1064-8011, Vol. 33, Nº. 4, 2019, págs. 1146-1155
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
We examined the effects of an 8-W circuit resistance training (RES) program using elastic bands and body weight on TCD4+ cell counts and anthropometry in patients with HIV. Patients (N = 21) receiving antiretroviral therapy were randomly assigned to resistance training (RES; n = 14) or control (CON; n = 7) groups. RES (3/W) consisted of training with elastic bands and bodyweight training focusing on major muscle groups. CON received standard care. Statistical analyses were performed using general linear models adjusted for age, sex, length of infection, and respective baseline measures. The primary outcome was TCD4+, and secondary outcomes were anthropometry indices. Tertiary assessments explored Pearson correlations surrounding the relationship between changes in anthropometry and TCD4+. We observed significant increases in TCD4+ count accompanying RES training (105.50 cells[middle dot]mm-3, 95% confidence interval [CI], 47.42-163.59), whereas CON significantly decreased (-41.01 cells[middle dot]mm-3, 95% CI, -126.78 to 44.76). Significant between-group differences were noted (p < 0.02; n2 = 0.42). We also observed significant reductions in fat mass for RES (1.18 kg, 95% CI = 1.80 to -0.56) vs. increased fat mass for CON (1.21 kg, 95% CI, 0.31 to 2.11). Significant between-group differences were noted (p = 0.001, n2 = 0.64). Similar effects were noted for lean body mass. No significant changes were observed for body mass. Significant correlations were observed for fat mass (r = -0.699, p = 0.001) and lean mass (r = 0.553, p = 0.017), but not body mass (r = -0.390, p = 0.109) vs. changes in TCD4+. Our results suggest that the RES program used in this study is effective for improving TCD4+ status and body composition in patients with HIV.
