Synthesis of Green Fluorescent Protein Chromophore Analogues for Interdisciplinary Learning for High School Students

• Shiho Numanoi ^[2] ; Makiko Hashimoto ^[3] ; Sonoko Hashimoto ^[3] ; Katsunori Kazawa ^[4] ; Ryo Sakaguchi ^[1] ; Kota Miyata ^[1] ; Rino Iwakami ^[1] ; Takahiro Mitome ^[1] ; Shintaro Anju ^[1] ; Ryo Shinotsuka ^[1] ; Toru Oba ^[1]
  1. [1] Utsunomiya University

     Utsunomiya University

     Japón

     
  2. [2] Otawara Girl’s High School, Japan
  3. [3] Kokugakuin University Tochigi High School, Japan
  4. [4] Higashi-Katsushika High School, Japan

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• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 96, Nº 3, 2019, págs. 503-507
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Interdisciplinary outreach activities with easy-to-implement experiments have been developed to enhance high school students’ interest in chemistry and their inquisitive minds with active learning strategies. The synthesis of a model chromophore of the green fluorescent protein was employed as a key motif. Students simply enjoyed observing changes in the substances as well as witnessing a variety of fluorescent emissions. They gradually realized the importance of molecular design in the understanding and development of chemistry, biology, physics, and medicine.