Viral teamwork pushes CRISPR to the breaking point

• Philip M. Nussenzweig ^[1] ; Luciano A. Marraffini ^[1]
  1. [1] Rockefeller University

     Rockefeller University

     Estados Unidos

     
• Localización: Cell, ISSN 0092-8674, Vol. 174, Nº. 4, 2018, págs. 772-774
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Viruses have evolved inhibitors to counteract the CRISPR immune response, but they are not fully potent and need some time to be expressed after the beginning of infection. In this issue of Cell, Borges et al. and Landsberger et al. show that sequential infection gradually immunosuppresses the host to allow effective CRISPR inhibition.