Enhancing therapy: it’s about time

• Myles Brown ^[1]
  1. [1] Dana–Farber Cancer Institute

     Dana–Farber Cancer Institute

     City of Boston, Estados Unidos

     
• Localización: Cell, ISSN 0092-8674, Vol. 174, Nº. 4, 2018, págs. 771-772
• Idioma: inglés
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• Resumen

  • How diet and obesity impact diurnal changes in physiology remains unclear. In this issue of Cell, Guan et al. report that diet-induced obesity modulates the activity of circadian gene enhancers including those regulating lipid metabolism and show that the efficacy of lipid-lowering drugs depends on the time of administration.