Clinical Uncertainties, Health Service Challenges, and Ethical Complexities of HIV "Test-and-Treat": A Systematic Review.

• Autores: Sonali P. Kulkarni, Kavita R. Shah, Karthik V. Sarma, Anish P. Mahajan
• Localización: American journal of public health, ISSN 0090-0036, Vol. 103, Nº. 6, 2013, págs. 14-23
• Idioma: inglés
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• Resumen

  • Despite the HIV "test-and-treat" strategy's promise, questions about its clinical rationale, operational feasibility, and ethical appropriateness have led to vigorous debate in the global HIV community. We performed a systematic review of the literature published between January 2009 and May 2012 using PubMed, SCOPUS, Global Health, Web of Science, BIOSIS, Cochrane CENTRAL, EBSCO Africa-Wide Information, and EBSCO CINAHL Plus databases to summarize clinical uncertainties, health service challenges, and ethical complexities that may affect the test-and-treat strategy's success. A thoughtful approach to research and implementation to address clinical and health service questions and meaningful community engagement regarding ethical complexities may bring us closer to safe, feasible, and effective test-and-treat implementation. [ABSTRACT FROM AUTHOR]