The article reports that until the 1930s, malaria was endemic throughout large swaths of the American South. A discussion of research which used a Poisson mixture model to analyze the decline of malaria at the county level in Alabama during the 1930s is presented. In the article the authors argue that the decline of malaria in the American South was not caused by population movement away from malarial areas or the decline of Southern tenant farming. Evidence is also provided for an alternate explanation that emphasizes the role of targeted New Deal–era public health interventions and the development of local-level public health infrastructure. Factors that led to the elimination of malaria in the southern U.S. are discussed.
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