Changing the guard at a prostate cancer SNP

• Michael Bulger ^[1]
  1. [1] University of Rochester Medical Center

     University of Rochester Medical Center

     City of Rochester, Estados Unidos

     
• Localización: Cell, ISSN 0092-8674, Vol. 174, Nº. 3, 2018, págs. 501-502
• Idioma: inglés
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• Resumen

  • The molecular underpinnings of a prostate-cancer-associated SNP are investigated in a pair of papers in this issue of Cell. Together, Gao et al. and Hua et al. paint a picture of competition between transcription factors that, in turn, toggle the function of a regulatory region from a promoter to an enhancer and induce a switch in noncoding RNA isoforms.