Resumen de Pigmented odontogenic keratocyst: report of a rare case and review of the literature
Carla-Isabelly Rodrigues-Fernandes, Paulo Rogério Ferreti Bonan, Elaine Judite de Amorim Carvalho, Celeste Sánchez-Romero, Oslei Paes de Almeida, Danyel Elias da Cruz Perez
Pigmented odontogenic keratocyst (OKC) is very rare and its etiology remains uncertain. To the best of our knowledge, only 9 cases of pigmented OKC have been published in English-language literature. This report describes a pigmented OKC in a 14-year-old black male patient. Radiographically, the lesion appeared as a well-circumscribed, unilocular, and radiolucent image. A surgical excision was performed. Histopathological examination revealed an OKC. Additionally, a brownish, sparsed, intracytoplasmic pigmentation was observed in the basal cell layer, which was positive for Fontana-Masson staining. Immunohistochemistry reactions revealed positive dendritic cells for S-100 protein, HMB45 and Melan A. No clinical and imaging signs of recurrence were observed after 24 months. In conclusion, melanin apparently does not represent a factor for distinct biological behavior in OKC.
