Use of bone scintigraphy in the early diagnosis of bisphosphonate related osteonecrosis of the jaw. Case report and review of the literature

• José-Darío Sánchez-López ^[2] ; Paolo Cariati ^[2] ; Jacobo Cambil-Martin ^[1] ; Mercedes Villegas-Calvo ^[3] ; María-Luisa Moreno-Martin ^[4]
  1. [1] Universidad de Granada

     Universidad de Granada

     Granada, España

     
  2. [2] Department of Oral an Maxillofacial Surgery. Universitary Hospital “Virgen de las Nieves”. Granada (Spain)
  3. [3] Department of Surgery. Universitary Hospital “Virgen de las Nieves”. Granada (Spain)
  4. [4] Department of Anestesiology. Universitary Hospital “Virgen de las Nieves”. Granada (Spain)

  Mostrar afiliaciones +
• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 10, Nº. 12 (December ), 2018, págs. 1235-1237
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • The main aim of the present report is to show the potential utility of bone scintigraphy for the diagnosis of jaw osteonecrosis. We report the history of a 62-year-old woman underwent breast cancer surgery in 2010. Moreover, patient received postoperative radiotherapy and chemotherapy. Intravenous bisphosphonates were also added to the treatment strategy to reduce the risk of bone metastasis. However, a hypermetabolic focus on left hemimandible was evidenced with a bone scintigraphy during follow up. After a careful study, the diagnosis of Bisphosphonate Related Ostneonecrosis of the Jaw (BRONJ) was carried out. This case highlights that bone scintigraphy may be extremely helpful for the early detection of BRONJ in high risk patient.