The article presents a historical overview of the development of the oral trivalent poliomyelitis vaccine by virologist Albert B. Sabin in the 1950s. Particular focus is given to the successful research collaboration between Sabin and Russian virologist Mikhail P. Chumakov to test the efficacy of the live oral vaccine, despite rising Cold War tensions between the U.S. and the Soviet Union. Other topics discussed include Sabin's rivalry with injectable poliovirus vaccine inventor Jonas Salk, U.S. Federal Bureau of Investigations (FBI) scrutiny of Sabin's political views, and the acceptance of the Soviet clinical trial results by scientists in Western countries and the World Health Organization (WHO). INSET: IN BRIEF.
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