The walrus and the carpenter: complex regulation of tumor immunity in colorectal cancer

• Grant Dewson ^[1] ; John Silke ^[1]
  1. [1] Walter and Eliza Hall Institute of Medical Research

     Walter and Eliza Hall Institute of Medical Research

     Australia

     
• Localización: Cell, ISSN 0092-8674, Vol. 174, Nº. 1, 2018, págs. 14-16
• Idioma: inglés
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• Resumen

  • Immune infiltration has been correlated with survival of patients with colorectal cancer. In this issue, Ziegler et al. reveal complex and unexpected connections between loss of STAT3, mitophagy, and the induction of an adaptive immune response that limits the growth of colorectal carcinoma.