SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018)

• A. Carmona-Bayonas ^[1] ; P. Jimenez-Fonseca ^[2] ; E. M. de Castro ^[3] ; E. Mata ^[4] ; M. Biosca ^[5] ; A. Custodio ^[6] ; J. Espinosa ^[7] ; E. G. Vázquez ^[8] ; F. Henao ^[9] ; Francisco Ayala de la Peña ^[1]
  1. [1] Hospital Morales Meseguer

     Hospital Morales Meseguer

     Murcia, España

     
  2. [2] Hospital Universitario Central de Asturias

     Hospital Universitario Central de Asturias

     Oviedo, España

     
  3. [3] Hospital Universitario Marqués de Valdecilla

     Hospital Universitario Marqués de Valdecilla

     Santander, España

     
  4. [4] Gobierno de Navarra

     Gobierno de Navarra

     Pamplona, España

     
  5. [5] Hospital Vall d'Hebron

     Hospital Vall d'Hebron

     Barcelona, España

     
  6. [6] Hospital Universitario La Paz

     Hospital Universitario La Paz

     Madrid, España

     
  7. [7] Hospital General de Ciudad Real

     Hospital General de Ciudad Real

     Ciudad Real, España

     
  8. [8] Hospital Virgen de la Arrixaca

     Hospital Virgen de la Arrixaca

     Murcia, España

     
  9. [9] Hospital Universitario Virgen Macarena

     Hospital Universitario Virgen Macarena

     Sevilla, España

     

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• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 21, Nº. 1 (January 2019), 2019, págs. 75-86
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Dialnet Métricas: 2 Citas
• Resumen

  • Febrile neutropenia (FN) is a common dose-limiting toxicity of chemotherapy, with a profound impact on the evolution of patients with cancer, due to the potential development of serious complications, mortality, delays, and decrease in treatment intensity. This article seeks to present an updated clinical guideline, with recommendations regarding the diagnosis, prevention, and treatment of febrile neutropenia in adults with solid tumors. The aspects covered include how to properly approach the risk of microbial resistances, epidemiological aspects, considerations about the initial empirical approach adapted to the risk, special situations, and prevention of complications. A decision-making algorithm is included for use in the emergency department based on a new, validated tool, the Clinical Index of Stable Febrile Neutropenia, which can be used in patients with solid tumors who appear stable in the initial phase of neutropenic infections, and can help detect those at high risk for complications in whom early discharge must be avoided.