Increasing T Cell Versatility with SUPRA CARs

• Autores: Yvonne Y. Chen
• Localización: Cell, ISSN 0092-8674, Vol. 173, Nº. 6, 2018, págs. 1316-1317
• Idioma: inglés
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• Resumen

  • Chimeric antigen receptor (CAR) T cells offer a promising treatment option for advanced cancers resistant to standard therapy. Here, Cho et al. report a split-CAR design that enables the engineering of multi-feature CAR-T cells, aiming to address current challenges limiting the safety and efficacy of CAR-T cells for cancer treatment.