Neurological disorders induced by liposomal amphotericin B in hematological patients

• Autores: Sara Gallardo Borge, Cristina Sangrador Pelluz, Ferran Vall-Llovera, Jordi Nicolás Picó
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 20, Nº. 5, 2018, págs. 274-276
• Idioma: inglés
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• Resumen

  • Liposomal amphotericin B (AmBL) has a toxicity profile with a low incidence of neurological disorders in relation to voriconazole. We present the case of a 71-yearold patient who presented an episode of visual hallucinations, disorientation, memory disorder and delirium after administration of AmBL. After carrying out a neurological study and a literature search of the possible triggering factors, the adverse reaction was attributed to AmBL, with a clear improvement in symptoms after the withdrawal of the antifungal